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Multicast is ef cient for group communications. The delivery of data to a group of users is preferable over multiple individual data connections between each pair of users. Each part of the system using multicast need not duplicate actions or data. A simpli ed view of how multicast can provide ef ciency in data delivery infrastructure is shown in Figure 10.1, where a single sender is delivering the same datastream to several wireless receivers. The gure also illustrates the communications ef ciencies that apply to xed and wireless links as well as the impact on the three mile system: . The rst mile, between the servers or senders and their respective network connections, typically the Internet with access provided by an Internet service provider (ISP) of some kind. Providing suf cient quality of service with reasonable connection costs is of paramount importance. . The middle mile, over which data passes from the remote source to the remote destination, analogous to major ISP core networks in the Internet core. Data traverses several links and devices, which it shares with other data streams. High-volume data ows and well-behaved connections, for instance employing friendly congestion control, are of paramount importance. . The last mile, between the user (or her/his network) and her/his communication access point, such as her/his local ISP with xed dialup or a cellular radio link with a wireless operator ISP. The costs and disadvantages of multicast are derived from the same axiom, that multicast is group communication. Thus ownership of costs, intellectual

In Proceedings of MILCOM 2001, pages 357 361, Vienna, Virginia, October 2001..

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Avoidance (HA) instead of the N or anxiety trait scales used by other investigators HA, however, is not a pure scale of the N factor but lies between the E and N dimensions, constituting a measure of introverted neuroticism It is de ned in the same way that Gray de nes trait anxiety: a sensitivity to cues associated with punishment and nonreward (frustration) and a tendency to avoid them Gray s (1982) model suggests that norepinephrine in the dorsal ascending noradrenergic system (DANA) originating in the locus coeruleus is the major neurotransmitter involved in anxiety, although high levels of serotonin may mediate the behavioral inhibition that is associated with high levels of anxiety Redmond (1977), from a psychiatric viewpoint, sees the DANA as an alarm system at lower levels and a panic provoker at high levels of activity.

One method of combining models is to use simple voting. For each record, each model supplies a prediction of either response (1) or nonresponse (0). We may then count the votes that each record obtains. For example, we are presently applying four classi cation algorithms to the promotion response problem. Hence, records may receive from 0 votes up to 4 votes predicting response. In this case, therefore, at the overall level, we may predict a positive response to the promotion based on any one of the following four criteria: A. B. C. D. Mail a promotion only if all four models predict response. Mail a promotion only if three or four models predict response. Mail a promotion only if at least two models predict response. Mail a promotion if any model predicts response.

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In contrast to these two theorists, Cloninger, Svrakic, and Przybeck (1993) proposed that high levels of serotonin activity underlie the trait of HA whereas norepinephrine activity is related to another trait called Reward Dependence In patients there has been little evidence of higher levels of the norepinephrine metabolite MHPG in anxiety patients compared to normals, although a more recent study by Spivak et al (1999) showed higher levels of MHPG in plasma of patients with combat-related posttraumatic stress disorder than in controls The alpha-2 receptor functions as a homeostatic regulator of the norepinephrine systems, tuning them down when excessive neurotransmitter levels are detected in the synapse Yohimbine is a antagonist to this receptor and therefore potentiates the activity of the norepinephrine system, just as a broken thermostat results in an overheated room.

After calculating the standard errors using Equations 51 and 52, the z score for Var_A for skewness is [0220/0346 =] 064, and the z score for kurtosis is 094 For Var_C (which was generated with skewness) the z score for skewness is 392, and the z score for kurtosis is 265 (Var_D also has a z score indicative of skewness, but it is due to the presence of an outlier, as becomes clear in a later section) Two-tailed alpha levels of 01 or 001 and visual inspection of the shape of the distribution are used to evaluate the signi cance of skewness and kurtosis with small to moderate samples.

Yohimbine increases MHPG levels and provokes panic attacks in patients with panic disorders, although it does not have these effects in normal controls (Charney & Heninger, 1986) Cameron et al (1996) replicated a previous result nding a decreased number of alpha-2 receptors in panic disorder One might extrapolate that MHPG should correlate with N or anxiety over the range in normals and other patient groups However, as noted earlier, high N in normals may resemble GAD more than panic disorder Heinz, Weingarten, Hommer, Wolkowitz, and Linnoila (1999) reported a high correlation between CSF MHPG and an anxiety scale in a combined group of abstinent alcoholics and normals A stress resistant group, de ned by N and similar measures, had lower plasma MHPG after a mild stressor than did a nonresistant (high-N) group (de Leeuwe, Hentschel, Tavenier, & Edelbroek, 1992).

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