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Ejaculatory Disorders Ejaculation distribution theory: Waldinger (1998) postulated that a dysregulation of the activation of some serotonergic receptor subtypes and/or genetic factors give rise to a biologic variation of the IELT in men According to this theory, men with lifelong PE belong to the extreme left side of the IELT curve [20] Recently such a biologic continuum of ejaculatory latency has been demonstrated in male rats and in a random population of men in different countries [14,21] The use of the 05% and 25% as accepted medical standards of disease de nition demonstrated that the 05% percentile equals a one minute IELT, and the 25% a 15 minute IELT Although both animal and human studies have indeed clearly demonstrated the existence of an ejaculation time distribution and a key role of the serotonergic system in the motoric output of ejaculation, the core neurobiologic factors of PE, including genetic factors, remain to be discovered

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It is assumed that the $3,000 cash on hand on December 31 is used in payment of liabilities The following liquidation data are given:

.

Assets Sold $64,000 60,000 62,000 $186,000

Draw a text box the same size as the button Type the text that will always appear at the head of the menu (We used the Maps of North America) Place the text box over the button In the Property inspector, choose Static Text from the Text Type drop-down list On the selected text layer, draw a text box at the top of the menu Specify the following settings in the expanded Property inspector:

Cash Received $41,000 37,000 54,000 $132,000

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Diagnosis of PE in clinical practice is not dif cult and is based on patient self-report, clinical history and examination ndings alone Men with PE should be evaluated with a detailed medical and sexual history, a physical examination, and appropriate investigations, to establish the true presenting complaint and any identifying obvious biologic causes, such as genital or lower urinary tract infection Treating physicians must interpret patient self-report of PE with some caution as both PE and non-PE men tend to somewhat overestimate their intravaginal ejaculatory latency time (IELT) compared to stopwatchrecorded IELT Pryor et al reported that non-PE men, however, overestimate their IELT to a larger extent than PE men, and that IELT estimations for PE men correlate reasonably well with stopwatch-recorded IELT [24] Although this observation has yet to be con rmed in other studies and differs from anecdotal observations of treating physicians, it does provide some evidence to suggest that PE patient estimation of IELT may be suf cient for the diagnosis of PE in clinical practice It is clinically relevant to distinguish lifelong and acquired PE Usually lifelong PE has a global manifestation, whereas acquired PE may occur situationally [25] However, in a research setting, objective measurement of IELT by stopwatch and subjectively validated, reliable and consistent patient-reported outcome measures (PROs) of ejaculatory control, sexual satisfaction, and bother/distress, are essential in studies assessing treatment [26 28] Although IELT self-estimations for PE men correlate reasonably well with stopwatch-recorded IELT and are suf cient for the clinical diagnosis of PE, there is no available data to suggest that men can reliably estimate the increases in IELT that occur with treatment Each of the three criteria above has been operationalized, although not always with consistency [7] Clinical trial outcome measures include the following: Intravaginal Ejaculation Latency Time (IELT): The length of time between penetration and ejaculation; the IELT forms the basis of most current clinical studies on PE [29] The IELT is measured with a stopwatch operated by the female partner, is expressed in.

Creditors Paid $24,000

$24,000

This research is still in its infancy Apart from behavioral studies, there is a need for standardization and more research is de nitely mandatory in this area There is no model available, for example, to investigate delayed or absent ejaculation or painful ejaculation, and the experimental equivalent of the male orgasm is lacking

Based on these data, the application of the computations already made results in the following payments to creditors and partners:

426 LIMITED PARTNERSHIPS Amount $41,000 37,000 54,000 $132,000 $21,000 Liabilities $21,000 Fox $20,000 7,000 15,000 3,000 16,000 $61,000 Green

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