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the quality of a study and amount of strength to give the recommendations. To obtain a perception of how your clinical trial may be rated and how you could strengthen it, you could evaluate it with the Strength-ofRecommendation Taxonomy (SORT). It can be downloaded without cost at http:// www.aafp.org/afpsort.xml.12 Once the study proposal has received IRB approval, I recommend you register your study with the U.S. National Library of Medicine (www.clinicaltrials.gov). The registration documents the various aspects of the study to ensure that the investigator does not change these if the results are different than anticipated. When submitting the manuscript to some journals, the author must report whether or not the study was registered at this web site.13 You will nd that many journals have limits on the length of manuscripts that they will publish, making it challenging to include features that various rating systems use to rate studies or to include the interesting observations made during the study. In my early years of publishing my studies, I made the mistake of not including some features that would have brought about a better rating for the studies. These studies subsequently received a lower rating in systematic reviews than they deserved and were possibly excluded because the features were not included. The reviewing authors justi ably assume that if it was not mentioned, it was not performed. I therefore encourage you to become knowledgeable about the features used to rate studies and include them in your manuscript.14

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This classic Indian curry is quick and easy to prepare. Serve with grilled meats, chicken, or fish, and a bowl of brown rice. Preparation Time: 15 minutes Cooking Time: 20 minutes Yield: 6 servings 21 2 cup (625 ml) cauliflower florets 1 tbsp (15 ml) soft margarine 1 medium onion, finely chopped 1 clove garlic, minced 1 tsp (5 ml) fresh ginger, grated 11 2 tsp (7 ml) ground coriander 1 2 tsp (7 ml) curry powder

N OT E If you are using Notepad as the text editor, ensure that the file is not saved as Acknowledgment.jsp.txt. To save the file as a JSP file, after entering the name of the file in the File name text box, be sure to select All Files from the Save as type list.

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Planning for scaling is not a step-by-step process. Use these techniques iteratively to improve your design. 1. Organize work into tiers. During the nineties, distributed programs grew from client/server, to three-tier, to n-tier. Basically this meant that you went from a client and server application, to a client and server and database, to a combination of clients and servers and databases. Think of these tiers as a part of your encapsulation process. Put work at one tier and keep it there. Assign responsibilities to each level of the solution and provide a strong interface on top of them. 2. Leverage JNDI and dynamic discovery. JNDI allows you to look up resources by a name or key. This type of indirection is similar to the separation of interface and implementation provided by OOP. Build the clients so that they have as little knowledge of the server as possible. If you can, make the addresses that the client uses dynamic so that you can change them as needed. This will allow you to plug in new server implementations without changing the client, just as polymorphism allows you to plug in new objects in place of others. This technique applies to Web Services as well as the other J2EE service mechanisms such as EJB and JMS. 3. Use EJBs and JMS destinations to hide work. You can think of an EJB as an interface to an unspecified amount of work. The same is true of a JMS destination, since it takes a message, and somehow the message is processed and a reply is sent. Any technology that goes over the network has the opportunity to work as an encapsulator for hiding implementation; try to use and document them this way.

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