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Most Fives both experience and talk about their emotional responses in a cerebral way rather than expressing them directly, saying what they think about something rather than how they feel. If a Five who was passed over for a promotion is asked how he or she feels, the Five may say, I think it was a political decision, rather than acknowledge feeling any anger or disappointment. Many Fives become confused when asked how they feel, having trouble distinguishing between a thought and an emotion.

protein actively moves molecules from a region of low concentration to a region of high concentration. The sodium-potassium pump establishes and maintains a concentration gradient such that sodium ions are concentrated on the outside of the cell, and potassium ions are concentrated on the inside of the cell. The sodium-potassium pump is an example of a cotransporter. The transport protein is called sodium-potassium ATPase when referring to its enzymatic activity (otherwise we can also just call it the sodium-potassium pump). Sodiumpotassium ATPase is an antiporter because it pumps sodium and potassium ions in opposite directions across the membrane. The mechanism of the sodiumpotassium pump has been studied extensively and is a good example of a biophysical process that involves a complex combination of conformational changes, binding of multiple ligands, and enzymatic activity. Such biophysical processes are not uncommon. Table 11-1 outlines the steps in the sodium-potassium pump mechanism. The protein has several binding sites for ligands. There are three sites that bind sodium ions, and two sites for binding potassium ions. There is also a site that binds ATP and catalyzes the hydrolysis of ATP. When the protein hydrolyzes ATP, it becomes phosphorylated. That is, the cleaved phosphate from the ATP becomes covalently attached to one of the amino acids in the protein. This phosphorylation is temporary and reversible. Phosphorylation of proteins is a common part of many biochemical processes. It can cause an otherwise hydrophobic amino acid to become charged or highly polar. This in turn will significantly alter the forces and various Gibbs energy interactions that determine the protein s secondary and tertiary structure. You can just imagine what can happen when a conformation that keeps the hydrophobic residues together and isolated from the aqueous environment, suddenly finds that one of the

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codecs are optimized for human speech Unfortunately, human speech is not always the only information that needs to be transmitted Within the telephone network, in addition to voice, all sorts of tones and beeps are transmitted not the kind of sounds produced naturally as part of human conversation These tones include fax tones, various tones such as busy tones, and the dual-tone multifrequency (DTMF) digits used in twostage dialing, voice mail retrieval, and other applications G711 can generally handle these tones and beeps quite well, because G711 samples the incoming signal without considering the origin of that signal Since G711 is the coder used in traditional telephony, such tones present no problem in circuit-switched networks The same tones cannot, however, be faithfully reproduced by lower-bandwidth codecs such as G7231 or G729.

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We see that the displacement is uniform, the velocity is constant, and the acceleration is zero during the rise. At the ends where the dwell meets the curve, however, we have an impractical condition. That is, as we go from the dwell (zero velocity) to a nite velocity, we have an instantaneous change in velocity, giving a theoretically in nite acceleration. This acceleration transmits high shock throughout the follower linkage, the magnitude of

If such tones are used as input, the output from those codecs can be unintelligible Many VoIP systems use gateways to provide an interface between the IP network and the circuit-switched network Incoming speech, either in analog form or coded according to G711, is converted to packetized speech at a lower bandwidth using an efficient coder It is then passed though the IP network to the destination The destination may be a native VoIP device or another gateway, in which case the packetized speech needs to be converted back to G711 In either case, if DTMF digits or other tones arrive at the ingress gateway, they need to be intercepted by the gateway and communicated to the far end in a different manner They should not be encoded in the same way as speech.

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