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Pregnancy may be the cause of primary amenorrhea even when the patient denies ever having had sexual intercourse

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Opening a .pdf file in new windowon the first page write the following code:-string url ... }note :- please import the namespace "using system.net" to use webclient.

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Patients with primary amenorrhea require a thorough history and physical examination to look for signs of the conditions noted above Headaches or visual field abnormalities implicate a hypothalamic or pituitary tumor Signs of pregnancy may be present Blood pressure abnormalities, acne, and hirsutism should be noted Short stature may be seen with an associated GH or thyroid hormone deficiency Short stature with manifestations of gonadal dysgenesis indicates Turner s syndrome (see below) Olfaction testing screens for Kallmann s syndrome Obesity and short stature may be signs of Cushing s syndrome Tall stature may be due to eunuchoidism or gigantism Hirsutism or virilization suggests excessive testosterone An external pelvic examination plus a rectal examination should be performed to assess hymenal patency and the presence of a uterus

B Hyperandrogenism (with Low or Normal FSH)

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Excess testosterone may be secreted by adrenal tumors or by adrenal hyperplasia caused by steroidogenic enzyme defects such as P450c21 deficiency (salt-wasting) or P450c11 deficiency (hypertension) Ovarian tumors or polycystic ovaries may also secrete excess testosterone Androgenic steroids may also cause this syndrome

You invoke a method on an object by writing the name of the object (boxObject) followed by the dot operator (.), the method name (DisplayBox), and the parameter list in parentheses (in this case, the list is empty). You ll see how to pass in values to initialize the member variables in Constructors later in this chapter.

The initial endocrine evaluation should include serum determinations of FSH, LH, PRL, testosterone, TSH, FT4, and hCG (pregnancy test) Patients who are virilized or hypertensive require serum electrolyte determinations and further hormonal evaluation Girls with low-normal FSH and LH especially those with high PRL levels are evaluated by MRI of the hypothalamus and pituitary Girls who have a normal

C Ovarian Causes (with High FSH)

Gonadal dysgenesis (Turner s syndrome and variants; see below) is a frequent cause of primary amenorrhea Ovarian failure due to autoimmunity is a common cause Rare deficiencies in certain ovarian steroidogenic enzymes are causes of

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An access modifier determines which class methods including methods of other classes can see and use a member variable or method within a class. Table 7-1 summarizes the C# access modifiers.

are normal have noncyclic secretion of gonadotropins resulting in anovulation Such women typically recover spontaneously but should have regular evaluations and a progestin withdrawal test about every 3 months to detect loss of estrogen effect PRL elevation due to any cause (see section on hyperprolactinemia) may cause amenorrhea Pituitary tumors or other lesions may cause hypopituitarism Corticosteroid excess of any cause suppresses gonadotropins

uterus and high FSH without the classic features of Turner s syndrome may require a karyotype to diagnose X chromosome mosaicism

Treatment of primary amenorrhea is directed at the underlying cause Girls with permanent hypogonadism are treated with estrogen replacement therapy (see below)

To get help on Mac OS X applications, you use the Apple Help Viewer (see figure 2.4), which you access from a Mac OS X program s Help menu. Mac OS X programs implement the Help menu as the rightmost Application menu and use the help system to present program information to the user. Most Mac OS X programs (Cocoa, Carbon, and Java) provide help in this manner, rather then using man pages. This is true of any GUI program written for Mac OS X, as well as GUI programs included with the OS.

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Torstveit MK et al Participation in leanness sports but not training volume is associated with menstrual dysfunction: a national survey of 1276 elite athletes and controls Br J Sports Med 2005 Mar;39(3):141 7 [PMID: 15728691] Warren MP et al The genetics, diagnosis and treatment of amenorrhea Minerva Ginecol 2004 Oct;56(5):437 55 [PMID: 15531861]

C Hyperandrogenism (with Low-Normal FSH)

Elevated serum levels of testosterone can cause hirsutism, virilization, and amenorrhea In PCOS, GnRH pulses are persistently rapid, favoring LH synthesis with excessive androgen secretion; reduced FSH secretion impairs follicular maturation Progesterone administration can slow the GnRH pulses, thus favoring FSH secretion that induces follicular maturation Rare causes include adrenal P450c21 deficiency, ovarian or adrenal malignancies, ectopic ACTH secretion by a malignancy, and Cushing s disease Anabolic steroids also cause amenorrhea

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