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ci c crosses coupled with the relatively small number of offspring) make these techniques of human chromosome mapping very dif cult. However, some progress has been made based on pedigrees, especially in assigning genes to the X chromosome. As the pedigree analysis in the previous chapter has shown, X chromosomal traits have unique patterns of inheritance, and loci on the X chromosome are easy to identify. Currently over four hundred loci are known to be on the X chromosome. It has been estimated, by several different methods, that between fty and one hundred thousand loci exist on human chromosomes. In later chapters, we will discuss several additional methods of human chromosomal mapping that use molecular genetic techniques.

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v (t) (V) vS (t) vC (t) 0 167 333 5 Time (ms)

247 Design of Diamond Tools [42, 43]

This response is plotted in Figure 426 The solution method outlined in the previous paragraphs can become quite complicated for circuits containing a large number of elements; in particular, one may need to solve higher-order differential equations if more than one energystorage element is present in the circuit A simpler and preferred method for the solution of AC circuits will be presented in the next section This brief section has provided a simple, but complete, illustration of the key elements of AC circuit analysis These can be summarized in the following statement:

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through the neutral line is zero, ie, Vn n = 0 The resulting per-phase circuit is shown in Figure 751 Using phase a for the calculations, we look for the quantity Pa = |I|2 RL

+ ~ ~ VS _

After determining that a human gene is X linked, the next problem is to determine the position of the locus on the X chromosome and the map units between loci. Sometimes we can do this with the proper pedigrees, if crossing over can be ascertained. An example of this grand-

and Pa = (8485)2 2 = 144 kW Since the circuit is balanced, the results for phases b and c are identical, and we have: PL = 3Pa = 432 kW

The McGraw Hill Companies, 2001

This fact is shown explicitly in Figure 751, where n and n are connected to each other directly Per-phase analysis for balanced circuits turn three-phase power calculations into a very simple exercise

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To design a diamond tool correctly, it is important to have knowledge of the damage patterns first Three patterns usually occur: normal wear, fracture and cleavage damage For preventing cleavage and reducing the normal wear, the diamond should be oriented before grinding To avoid a fracture, the cutting edge and tool nose should be strengthened [42, 43] Design principles The diamond tool should be of a high quality and have a long tool life It is also necessary that a suitable raw diamond of a high utilization ratio, and is easy to grind, is chosen Design sequence The design sequence is as follows: 1 Determine the geometric parameters of the tool 2 Orient the diamond crystal, and draw the orientation figure 3 Determine the grinding sequence and the grinding direction of every operation (technological regulation) 4 Stipulate the requirement for the raw diamond, the cutting edge and the roughness of the tool faces 5 Obtain the working drawing

Balanced Wye Loads In the previous section we performed some power computations for a purely resistive balanced wye load We shall now generalize those results for an arbitrary balanced complex load Consider again the circuit of Figure 746, where now the balanced load consists of the three complex impedances Za = Zb = Zc = Zy = |Zy | (758)

Dihybrid at prophase (mitosis)

From the diagram of Figure 746, it can be veri ed that each impedance sees the corresponding phase voltage across itself; thus, since the currents Ia , Ib , and Ic have the same rms value, I , the phase angles of the currents will differ by 120 It is therefore possible to compute the power for each phase by considering the phase voltage (equal to the load voltage) for each impedance, and the associated line current Let us denote the complex power for each phase by S: S = V I so that S = P + jQ = V I cos + j V I sin (760) (759)

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